The clinical stage is your doctor’s best estimate of the extent of your disease, based on the results of the physical exam (including DRE), laboratory tests, prostate biopsy, and any imaging tests you’ve had.
The pathologic stage, which is based on the surgery and examination of the removed tissue
1. American Cancer Society. Prostate Cancer Stages. https://www.cancer.org/cancer/... . Accessed on 22 October 2021.