Treatment options by stage

Treatment options by stage

Standard treatments to control the prostate cancer.

  • Active surveillance.
  • Radical prostatectomy, usually with pelvic lymphadenectomy.
  • External beam radiotherapy.
  • Brachytherapy – interstitial implants of radioactive seeds.
  • Clinical trials of new therapies may be an option.

Standard treatments to control the prostate cancer.

  • Active surveillance.
  • Radical prostatectomy, usually with pelvic lymphadenectomy. Radiotherapy may also be given after surgery.
  • External beam radiotherapy. Hormone therapy may be recommended after the radiotherapy.
  • Brachytherapy.
  • Clinical trials with new therapies may be an option.

Treatments usually include a combination of brachytherapy, radiotherapy, hormonal therapy and surgery to alleviate urinary symptoms. Patients at stage III are at high risk for metastatic spread of prostate cancer. The treatment goal is to maximally destroy the cancer and reduce the possibility of further spread. Some patients may have untraceable metastatic spread which requires indefinite systemic hormonal treatment.

  • External radiotherapy. Hormone therapy is consistently recommended with and after the radiotherapy.
  • Hormone therapy, usually in conjunction with other treatment method and may be continued indefinitely.
  • Radical prostatectomy is uncommon and performed only in selected patients and typically followed by external radiation and hormone therapy.
  • Brachytherapy and external radiotherapy routinely together with hormone therapy.
  • Transurethral resection of the prostate (TURP) to alleviate urinary symptoms.
  • Watchful waiting (observation).
  • Clinical trials with new therapies may be an option.

The goals of treatment focus on slowing disease progression, improving quality of life and increasing survival time.

  • Hormone therapy.
  • Chemotherapy in combination with hormone therapy.
  • Palliative external radiotherapy to control symptoms or prevent fracture of affected by cancer bones.
  • Palliative internal radiotherapy.
  • Transurethral resection of the prostate (TURP).
  • Watchful waiting (observation).
  1. American Cancer Society. Initial Treatment of Prostate Cancer, by Stage and Risk Group. https://www.cancer.org/cancer/prostate-cancer/treating/by-stage.html. Accessed on 22 October 2021.

References

NHS. Psoriasis overview. Available at: https://www.nhs.uk/conditions/psoriasis/ Accessed: June 2020.
National Psoriasis Foundation. Guttate psoriasis. Available at: https://www.psoriasis.org/about-psoriasis/types/guttate Accessed: June 2020.
British Association of Dermatologists patient hub; Psoriasis: an overview. Available at: https://www.skinhealthinfo.org.uk/condition/psoriasis/ Accessed: June 2020.
DermNet NZ. Guttate psoriasis. Available at: https://dermnetnz.org/topics/guttate-psoriasis/ Accessed: June 2020.
National Psoriasis Foundation. About psoriatic arthritis. Available at: https://www.psoriasis.org/about-psoriatic-arthritis Accessed: June 2020.
WebMD. Skin problems and treatments: psoriasis. How severe is your psoriasis? Available at: https://www.webmd.com/skin-problems-and-treatments/psoriasis/how-severe-your-psoriasis Accessed: June 2020.
Walsh JA, et al. Psoriasis (Auckl). 2018; 8:65–74.
GP notebook. NAPSI. Available at: https://gpnotebook.com/simplepage.cfm?ID=x20121104114703605084 Accessed: June 2020.
Logo Janssen | Pharmaceutical Companies of Johnson & Johnson